Riedels thyroiditis definition of riedels thyroiditis. We describe herein ct and mr imaging features of riedels thyroiditis in a case of. We present a case of a 59yearold africancaribbean man who presented with a rapidly growing hard neck mass, a hoarse. Riedels thyroiditis is a rare benign pathology of unclear etiology, characterized by a densely fibrotic inflammatory process involving the thyroid gland and the adjacent neck tissues. There are many possible causes of thyroiditis see thyroiditis brochure.
Hashimotos thyroiditis, also known as chronic lymphocytic thyroiditis, is the most. The thyroid becomes enlarged, often asymmetrically, to form a firm, hard mass of scar. The exact cause of riedels thyroiditis remains unknown, and no specific treatment is available beyond limited resection of the thyroid gland to relieve the symptoms of tracheal or esophageal compression. Proteomic approach used in the diagnosis of riedels. Riedels thyroiditis is a form of thyroiditis that occurs in middle aged or elderly women. Infectious thyroiditis is a rare condition, usually the result of bacterial invasion of the gland. The exact cause of riedels thyroiditis remains unknown, and no specific treatment is available beyond limited resection of the thyroid. They include conditions that cause acute illness with severe thyroid pain eg, subacute thyroiditis and infectious thyroiditis and conditions in which there is no clinically evident inflammation and the illness is manifested primarily by thyroid dysfunction or goiter eg, painless thyroiditis and fibrous riedel s thyroiditis. Riedels thyroiditis is a rare fibrotic condition that results in the destruction of the thyroid and infiltration into surrounding tissues. Riedel thyroiditis synonyms, riedel thyroiditis antonyms. Riedels thyroiditis treated with tamoxifen article pdf available in croatian medical journal 442. Genetic background of riedels thyroiditis remains unknown.
Riedel thyroiditis, or riedels thyroiditis rt, is a rare, chronic inflammatory disease of the thyroid gland characterized by a dense fibrosis that replaces normal thyroid parenchyma. In carcinoma of thyroid gland, it appears hyperdense. Riedel s thyroiditis is a form of thyroiditis that occurs in middle aged or elderly women. Riedel s thyroiditis is a rare entity in which fibrous tissue replaces the thyroid gland and tends to extend into the surrounding tissues. Riedels thyroiditis is a rare fibrotic condition that results in destruction of the thyroid and infiltration into surrounding tissues. Thyroid uk other thyroid disorders riedels thyroiditis. This fibrotic process spreads to tissue in the neck outside the thyroid capsule. A 46yearold woman with clinical diagnosis of riedel s thyroiditis was admitted to our department, presenting with dyspnea, dysphagia, fatigue, and hoarseness. The term thyroiditis refers to inflammation of the thyroid gland. At operation the thyroid gland was extensively fibrosed and not resectable, frozen section showed fibrous replacement. Riedels thyroiditis is a rare disease with an approximate incidence of 1. Riedel s thyroiditis is a chronic form of thyroiditis. The main features of riedels thyroiditis are summarized in table 4418 fig. Blood test for antithyroid antibodies is positive in many cases of riedels thyroiditis.
Riedels thyroiditis is a rare inflammatory process involving the thyroid and surrounding cervical tissues and is associated with various for we use cookies to enhance your experience on our website. Riedels thyroiditis, also known as riedels struma or invasive fibrous thyroiditis, is a rare chronic inflam matory disease of the. Riedels struma, also known as invasive fibrous thyroiditis, is a rare disorder of unknown etiology in which fibrous tissue replaces the normal thyroid gland and extends into adjacent tissues. Herein, we describe our results of studies on genes expression levels in riedel s thyroiditis. Clinically this is a hard, palpable goiter, which could cause pain, compressive symptoms, and affect adjacent structures as the parathyroid glands, musculature in the neck and cause. We report the case of 48year old woman with riedel s thyroiditis who has presented unusual course of disease with nonspecific cervical discomfort, though as with no pain andor no compression symptoms. Riedels thyroiditis is a chronic form of thyroiditis. Riedels thyroiditis article about riedels thyroiditis. Acute and subacute, and riedels thyroiditis rupendra t. Riedels thyroiditis article about riedels thyroiditis by.
Genetic background of riedel s thyroiditis remains unknown. Riedel s thyroiditis, known as invasive fibrous thyroiditis, is a very rare form of chronic thyroiditis. Riedel thyroiditis, or riedel s thyroiditis rt, is a rare, chronic inflammatory disease of the thyroid gland characterized by a dense fibrosis that replaces normal thyroid parenchyma. Synonyms for riedel s thyroiditis in free thesaurus. The fibrotic process invades adjacent structures of the neck and extends beyond the thyroid capsule. Surgical biopsy of the thyroid gland will differentiate. In mri study reveals riedels thyroid to be hypodense. Symptoms include pain upon swallowing or moving the head. Surgical treatment for riedels thyroiditis koreamed synapse. Mar 07, 2017 riedel thyroiditis, or riedel s thyroiditis rt, is a rare, chronic inflammatory disease of the thyroid gland characterized by a dense fibrosis that replaces normal thyroid parenchyma. Forms of the disease are hashimotos thyroiditis, the most common cause of hypothyroidism in the us, postpartum thyroiditis, subacute thyroiditis, silent thyroiditis, druginduced thyroiditis, radiationinduced thyroiditis, acute thyroiditis, and riedels thyroiditis. Riedels thyroiditis is a rare entity consisting of a fibrotic process of the thyroid which can generate gland destruction, infiltration of cervical structures and even. Riedels thyroiditis is a rare benign pathology of unclear eti. By continuing to use our website, you are agreeing to our use of cookies.
Riedels thyroiditis riedels thyroiditis is a very rare form of thyroid disease which causes a dense fibrosis scarring of the connective tissue that replaces normal thyroid tissue. There is a paucity of robust epidemiological data because the worlds literature consists primarily of case reports and small case series. Riedels thyroiditis synonyms, riedels thyroiditis antonyms. Most recently all these pathologies are considered as manifestations of the same pathology known as igg4. It is often a multiorgan disease affecting pancreas, liver, kidney, salivary and orbital tissues and retroperitoneum. She suffered from bilateral neck pain, which radiated to both lower jaws. A fifty two year old female underwent attempted thyroidectomy for a progressively enlarging cervical swelling. Riedels thyroiditis, is a chronic form of thyroiditis. The exact cause of riedels thyroiditis remains unknown. It is hard to make the diagnosis without surgical biopsy.
Full text is available as a scanned copy of the original print version. Riedel thyroiditis article about riedel thyroiditis by. It is characterized by a replacement of the normal thyroid parenchyma by a dense fibrosis that invades adjacent structures of the neck and extends beyond the thyroid capsule. Synonyms for riedels thyroiditis in free thesaurus. It is often a multiorgan disease affecting pancreas, liver, kidney, salivary and orbital tissues and. Thyroiditis journal of association of physicians of india. It is now believed that riedel s thyroiditis is one manifestation of a systemic disease that can affect many organ systems called igg4related disease. The diagnosis of hashimotos thyroiditis may be made when patients present with symptoms of hypothyroidism, often accompanied by a goiter an enlarged thyroid gland on physical examination, and laboratory testing of. Riedel s thyroiditis synonyms, riedel s thyroiditis pronunciation, riedel s thyroiditis translation, english dictionary definition of riedel s thyroiditis. Riedel thyroiditis is a very rare form of autoimmune thyroiditis. Corticosteroid therapy in riedel s thyroiditis 817 corticosteroid therapy in riedel s thyroiditis bvaidya, peharris, pbarrett, pkendalltaylor royal victoria infirmary, newcastle upon tyne, nei 4lp, uk department of medicine endocrinology bvaidya peharris pkendalltaylor department of pathology pbarrett correspondence to bvaidya, department of. Sep, 2012 hashimotos thyroiditis and papillary form carcinoma of thyroid gland may have fibrotic infiltration but not to the extent that is observed in riedels thyroiditis.
Riedels thyroiditis is a rare chronic inflammatory disease of the thyroid gland first recognized by bernhard riedel in 1893. Riedels thyroiditis is a rare fibrotic condition that results in destruction of the thyroid and infiltra. Riedels thyroiditis an overview sciencedirect topics. Riedels thyroiditis synonyms, riedels thyroiditis pronunciation, riedels thyroiditis translation, english dictionary definition of riedels thyroiditis. In order to clarify the clinical and pathologic features of this rare disorder, a recent case of riedels thyroiditis is presented, 6 additional cases from the surgical pathology files of the cleveland clinic foundation are reported, and the 178 cases. Riedels thyroiditis associated with hypothyroidism and. Riedel s thyroiditis is a rare disease with an approximate incidence of 1. Riedel thyroiditis article about riedel thyroiditis by the.
Riedels thyroiditis on the web most recent articles. It is often a multiorgan disease affecting pancreas, liver, kidney. For information on thyroid patient support organizations, please visit the patient support links section on the ata website at. Abstractriedel s thyroiditis is an extremely rare disease that is difficult to diagnose.
Forms of the disease are hashimoto s thyroiditis, the most common cause of hypothyroidism in the us, postpartum thyroiditis, subacute thyroiditis, silent thyroiditis, druginduced thyroiditis, radiationinduced thyroiditis, acute thyroiditis, and riedel s thyroiditis. Since riedels thyroiditis is a rare disease, there is lack of research for specific therapy. This case is important as it highlights the difficulties in managing complex riedels thyroiditis patients. Riedels thyroiditis involves infiltration and attachment of surrounding tissue which is not present in other forms. Hashimotos thyroiditis lymphocytic thyroiditis how is the diagnosis of hashimotos thyroiditis made. Riedels thyroiditis is a very rare form of thyroid disease which causes a dense fibrosis scarring of the connective tissue that replaces normal thyroid tissue. Although the condition is benign and selflimiting, its importance lies in its ability to clinically mimic carcinoma. Jun 17, 2016 riedel s thyroiditis is a rare benign pathology of unclear etiology, characterized by a densely fibrotic inflammatory process involving the thyroid gland and the adjacent neck tissues. Full text get a printable copy pdf file of the complete article 445k, or click on a page image below to browse page by page. Get a printable copy pdf file of the complete article 706k, or click on a page image below to browse page by page.
It is now believed that riedels thyroiditis is one manifestation of a systemic disease that can affect many organ systems called igg4related disease. Riedels thyroiditis masquerading as anaplastic thyroid. We present a case of riedels thyroiditis in a 52yearold female with past history of hashimotos thyroiditis. This article is from journal of the korean surgical society, volume 82.
Thyroiditis is a group of disorders that all cause thyroidal inflammation. In this article, we describe an unusual case of riedel s thyroiditis and discuss its imagery and pathology. The term thyroiditis encompasses a diverse group of disorders characterized by some form of thyroid inflammation. We present a case of riedel s thyroiditis in a 52yearold female with past history of hashimoto s thyroiditis. We report the case of 48year old woman with riedels thyroiditis who has presented unusual course of disease with nonspecific cervical discomfort, though as with no pain andor no compression symptoms. Invasive fibrous riedel s thyroiditis is a rare thyroid condition of unknown origin that may be associated with inflammatory fibrosclerosing processes elsewhere in the body. This feature differentiates rt from other inflammatory or. Links to pubmed are also available for selected references. The patient was given a short course of postoperative corticosteroid therapy and was maintained on thyroid replacement therapy. Riedels thyroiditis, known as invasive fibrous thyroiditis, is a very rare form of chronic thyroiditis. In this article, we describe an unusual case of riedels thyroiditis and discuss its imagery and pathology.
Treatment hashimotos thyroiditis with hypothyroidism is best treated with lthyroxine replacement. The process extends to adjacent structures, making any surgical intervention very difficult and potentially harmful. Riedels thyroiditis a case report with genes expression. Usually this is a part of a multifocal, systemic, fibrotic syndrome which includes biliary tract sclerosis, sclerosing cervicitis, and sjogren sydrome. This fibrotic process spreads to tissue in the neck outside the. Riedels thyroiditis, also called riedels struma is a chronic form of thyroiditis it is now believed that riedels thyroiditis is one manifestation of a systemic disease that can affect many organ systems called igg4related disease.
Herein, we describe our results of studies on genes expression levels in riedels thyroiditis. Thyroiditis inflammation of the thyroid gland caused by nonspecific infection for example, staphylococcosis, specific infection tuberculosis, poisoning by lead or carbon monoxide, or autoimmune diseases. Riedels thyroiditis is an often disabling disease with clinical and histologic similarity to several other fibrous inflammatory disorders. This disease was first recognized in 1896 by bernhard riedel, who described two patients with tracheal compromise secondary to a hard fibrotic thyroid. The operative incidence at the mayo clinic rochester, mn, usa was 0. Riedels thyroiditis is a chronic sclerosing replacement of the gland that is exceedingly rare. A misdiagnosed riedels thyroiditis successfully treated by. Riedels thyroiditis is exceedingly rare, occurring in some series one 50th as frequently as hashimotos thyroiditis 1115. They include conditions that cause acute illness with severe thyroid pain eg, subacute thyroiditis and infectious thyroiditis and conditions in which there is no clinically evident inflammation and the illness is manifested primarily by thyroid dysfunction or. Riedels thyroiditis is a rare entity in which fibrous tissue replaces the thyroid gland and tends to extend into the surrounding tissues. It is important to distinguish riedels thyroiditis from thyroid carcinoma.
Riedels thyroiditis fibrous thyroiditis, rt is an extremely rare form of thyroiditis, leading to a gradual parenchymal transformation to connective tissue. Riedel s thyroiditis, also called riedel s struma is a chronic form of thyroiditis. Riedels thyroiditis is a rare type of chronic thyroiditis, associated with fibroinflammatory process and invasion into surrounding tissues, leading to compressive symptoms. A misdiagnosed riedels thyroiditis successfully treated. Extensive stony hard fibrosis involving a goitrous thyroid gland and infiltration into adjacent muscle and other structures, obliterating tissue planes at surgery. Few epidemiologic studies of sat have been reported. Riedels thyroiditis is a rare thyroid disease characterized by dense fibrous tissues that replace the thyroid gland and invade the adjacent structures that can mimic thyroid malignancy. Thyroid riedel thyroiditis riedel thyroiditis is an extremely rare as prevalent as hashimoto s fibroinflammatory condition of the thyroid, first described in the mid to late1800s and now thought to be igg4 related. Riedel thyroiditis, also called struma fibrosa, or ligneous thyroiditis, extremely rare form of chronic inflammation of the thyroid gland, in which the glandular tissues assume a densely fibrous structure, interfering with production of thyroid hormone and compressing the adjacent trachea and esophagus.
It is sometimes considered as a manifestation of a wider systemic disease with fibrosis of the retroperitoneum, mediastinum, as well as lymphocytic infiltration of extraocular orbital muscles, salivary and lacrimal glands 4. Abstractriedels thyroiditis is an extremely rare disease that is difficult to diagnose. Riedels thyroiditis definition of riedels thyroiditis by. We discuss the presentation, investigation and management of this very rare condition. Antithyroid drugs carbimazole, methimazole and propylthiouracil are initial treatment of choice in graves disease. Laboratory studies on patients with different forms of chronic thyroiditis no. The case also highlights the novel use of rituximab in the. Riedel thyroiditis is a rare chronic inflammatory disease of the thyroid gland and is characterized by the invasion of the thyroid gland and surrounding structures by dense fibrous tissues 1, 2. Riedels thyroiditis is a rare disorder of unknown etiology and may be seen isolated or as a part of multifocal fibrosclerosis. We present the case of a 36 year old woman with riedels thyroiditis which developed into hypothyroidism and hypoparathyroidism. Reports about imaging features of riedels thyroiditis are limited in the radiologic literature.
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